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This book presents solutions to missing data problems through explicit or noniterative sampling calculation of Bayesian posteriors, based on the inver...Lees meer
Helping you become a skillful "simulator," this book provides broad coverage of the drug development process, from drug discovery to preclinical and c...Lees meer
Like the well-regarded and bestselling second edition, Sample Size Calculations in Clinical Research, Third Edition , presents statistical procedures ...Lees meer
Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for ea...Lees meer
Drawing from the authors' courses on the subject as well as the first author's more than 30 years working in the pharmaceutical industry, Clinical Tri...Lees meer
This text describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinical trials as well as the practical aspe...Lees meer
This text describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinical trials as well as the practical aspe...Lees meer
Quantitative Methodologies and Process for Safety Monitoring and Ongoing Benefit Risk Evaluation provides a comprehensive coverage on safety monitorin...Lees meer
Drug development sponsors cannot run individual trials for all products in all indications. This results in missed opportunities. Clinical trial progr...Lees meer
This book concentrates on the biostatistics component of clinical trials. This new, second edition is updated throughout and includes three new chapte...Lees meer
This text gives graduate students with diverse backgrounds across the health, medical, social, and mathematical sciences a solid, unified foundation i...Lees meer
This book covers classic epidemiological designs that use a reference/control group, including case-control, case-cohort, nested case-control and vari...Lees meer
A disease is defined as rare if the prevalence is fewer than 200,000 in the United States. It is estimated that there are more than 7,000 rare disease...Lees meer
Bayesian methods have emerged as the driving force for methodological development in drug development. This edited book provides broad coverage of Bay...Lees meer
As the development of medicines has become more globalized, the geographic variations in the efficacy and safety of pharmaceutical products need to be...Lees meer
Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Fourth Edition focuses on the statistical aspects ofmedicine with a medical...Lees meer
Longitudinal studies often investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest. An example ...Lees meer
Comparative effectiveness research has become essential for shaping regulatory policy, informing economic evaluations, and guiding treatment standardi...Lees meer
Incidence rates are counts divided by person-time; mortality rates are a well-known example. Analysis of Incidence Rates offers a detailed discussion ...Lees meer
With ever-rising healthcare costs, evidence generation through Health Economics and Outcomes Research (HEOR) plays an increasingly important role in d...Lees meer
Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare covers exciting developments at the intersection of computer science ...Lees meer
Methodologies for Biosimilar Product Development covers the practical and challenging issues that are commonly encountered during the development, rev...Lees meer
The concepts of estimands, analyses (estimators), and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these t...Lees meer
With ever-rising healthcare costs, evidence generation through Health Economics and Outcomes Research (HEOR) plays an increasingly important role in d...Lees meer