Optimal Design for Nonlinear Response Models

Valerii V Fedorov, Sergei L Leonov

• Paperback | Engels | Chapman & Hall/CRC Biostatistics | nr. 53
• Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopha... Lees meer

Fundamental Concepts for New Clinical Trialists

Scott Evans, Naitee Ting

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Fundamental Concepts for New Clinical Trialists describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinica... Lees meer

Benefit-Risk Assessment Methods in Medical Product Development

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Guides You on the Development and Implementation of B-R Evaluations Benefit-Risk Assessment Methods in Medical Product Development: Bridging Qualitati... Lees meer

Quantitative Drug Safety and Benefit Risk Evaluation

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• Quantitative Methodologies and Process for Safety Monitoring and Ongoing Benefit Risk Evaluation provides a comprehensive coverage on safety monitorin... Lees meer

Monte Carlo Simulation for the Pharmaceutical Industry

Mark Chang

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics | nr. 36
• Helping you become a creative, logical thinker and skillful "simulator," Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms,... Lees meer

Bayesian Missing Data Problems

Ming T Tan, Guo-Liang Tian, Kai Wang Ng

• Paperback | Engels | Chapman & Hall/CRC Biostatistics | nr. 32
• Bayesian Missing Data Problems: EM, Data Augmentation and Noniterative Computation presents solutions to missing data problems through explicit or non... Lees meer

Clinical Trial Methodology

Karl E Peace, Ding-Geng (Din) Chen

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics | nr. 35
• Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clini... Lees meer

Statistics in Drug Research

Shein-Chung Chow, Jun Shao

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics | nr. 10
• Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for ea... Lees meer

Sample Size Calculations in Clinical Research

Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Praise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization a... Lees meer

Controlled Epidemiological Studies

Marie Reilly

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• This book covers classic epidemiological designs that use a reference/control group, including case-control, case-cohort, nested case-control and vari... Lees meer

Bayesian Applications in Pharmaceutical Development

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• The cost for bringing new medicine from discovery to market has nearly doubled in the last decade and has now reached $2.6 billion. There is an urgent... Lees meer

Inference Principles for Biostatisticians

Ian C Marschner

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Designed for students training to become biostatisticians as well as practicing biostatisticians, Inference Principles for Biostatisticians presents t... Lees meer

Design and Analysis of Bridging Studies

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• As the development of medicines has become more globalized, the geographic variations in the efficacy and safety of pharmaceutical products need to be... Lees meer

Platform Trial Designs in Drug Development

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Platform trials test multiple therapies in one indication, one therapy for multiple indications, or both. These novel clinical trial designs can drama... Lees meer

Model-Assisted Bayesian Designs for Dose Finding and Optimization

Ying Yuan, Ruitao Lin, J Jack Lee

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• Bayesian adaptive designs provide a critical approach to improve the efficiency and success of drug development that has been embraced by the US Food ... Lees meer

Bayesian Methods in Pharmaceutical Research

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages ... Lees meer

Statistical Design, Monitoring, and Analysis of Clinical Trials

Weichung Joe Shih, Joseph Aisner

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• This book concentrates on the biostatistics component of clinical trials. This new, second edition is updated throughout and includes three new chapte... Lees meer

Statistical Methods for Drug Safety

Robert D Gibbons, Anup Amatya

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Explore Important Tools for High-Quality Work in Pharmaceutical Safety Statistical Methods for Drug Safety presents a wide variety of statistical appr... Lees meer

Randomized Phase II Cancer Clinical Trials

Sin-Ho Jung

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics | nr. 55
• In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. Thi... Lees meer

Drug Development for Rare Diseases

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• A disease is defined as rare if the prevalence is fewer than 200,000 in the United States. It is estimated that there are more than 7,000 rare disease... Lees meer

Methodologies in Biosimilar Product Development

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• Methodologies for Biosimilar Product Development covers the practical and challenging issues that are commonly encountered during the development, rev... Lees meer

Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare

Mark Chang

• Hardcover | Engels | Chapman & Hall/CRC Biostatistics
• Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare covers exciting developments at the intersection of computer science ... Lees meer

Exposure-Response Modeling

Jixian Wang

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Discover the Latest Statistical Approaches for Modeling Exposure-Response Relationships Written by an applied statistician with extensive practical ex... Lees meer

Design and Analysis of Bioavailability and Bioequivalence Studies

Shein-Chung Chow, Jen-Pei Liu

• Paperback | Engels | Chapman & Hall/CRC Biostatistics
• Preeminent Experts Update a Well-Respected Book Taking into account the regulatory and scientific developments that have occurred since the second edi... Lees meer