The patient with sepsis provides a major challenge to the hospital acute team and septic shock is the commonest cause of admission to General Critical Care Units in the industrialized world. The incidence of sepsis is also increasing, in part due to the more complex patient case mix which is a feature of modern hospital practice. Sepsis is a multi-factorial disease process and this volume provides comprehensive and in-depth reviews of both the basic science and more practical aspects of patient management. Coverage includes detailed information on the epidemiology and genetics of sepsis as well as the metabolic and cardiovascular responses to infection.
The book also reviews infectious disease in relation to sepsis, haematological aspects of sepsis, as well as the currently controversial areas of clinical trial design in sepsis and protocol-driven care. In addition, a specific chapter, with illustrated cases, draws practical lessons and offers useful management tips.
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